Chrysophanol是什么
WebFeb 23, 2024 · Chrysophanol is an anthraquinone with purported potent antitumor effects [11, 12]. How chrysophanol exerts its anticancer effects in meningioma is unknown. To … WebMar 14, 2024 · of chrysophanol in combination with other drugs can reduce toxicity and enhance efficacy. Summary Chrysophanol can be used in many diseases. Future research direc-tions include how the concentration of chrysophanol affects pharmacological effects and toxicity; the mechanism of synergy between chrysophanol …
Chrysophanol是什么
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WebNov 13, 2024 · Chrysophanol (CHR), also well-known as Rhei radix et rhizome, is a crucial component in traditional Chinese medicine. It has been widely studied as a potential treatment for many diseases due to its anti-inflammatory effects. However, there are very few studies to establish the potential therapeutic effect of CHR in cell and animal models … WebIn Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. Tumorigenicity. Several anthranoid derivatives (notably the aglycones aloe-emodin, chrysophanol, emodin, and physicon) are genotoxic in bacterial and/or mammalian test systems [3], and two anthranoid compounds (the synthetic laxative dantron and the naturally occurring l …
Chrysophanol, also known as chrysophanic acid, is a fungal isolate and a natural anthraquinone. It is a C-3 methyl substituted chrysazin of the trihydroxyanthraquinone family. Chrysophanol (other names; 1,8-dihydroxy-3-methyl-anthraquinone and chrysophanic acid) was found commonly … See more Chrysophanol was first noted from Rheum rhabarbarum which is a plant belonging to the Polygonaceae family. It has since been discovered to be present in various families such as Liliaceae, Meliaceae, Asphodelaceae … See more Chrysophanol can act as an antineoplastic drug. This has been shown in multiple organisms. It has been reported that chrysophanol causes necrosis-like cell death in renal … See more Chrysophanol has been shown to be able to be co-administered with atorvastatin, to lower cholesterol levels. This is due to the different … See more Chrysophanol has been shown to exhibit a variety of effects. It was shown in 2015 to lower cholesterol and triglyceride levels in zebrafish, as well as increase the frequency of … See more Chrysophanol can alleviate diabetic nephropathy by inactivating TGF-β/EMT signalling. It also has the potential to protect bronchial cells from cigarette smoke extract by … See more Chrysophanol is naturally made by a variety of plant species. The most intake is from consumption of rhubarb. See more Anthraquinones, chrysophanol derivatives among them, have been shown to be hepatotoxic. They can cause apoptosis in normal human liver cells. Chrysophanol derivatives such as … See more WebChrysophanic acid (Chrysophanol) is a member of the anthraquinone family abundant in rhubarb, a widely used herb for obesity treatment in Traditional Korean Medicine. Chrysophanol has been shown to induce cell death in different types of cancer cells. Chrysophanol inhibits EGF-induced phosphorylation of EGFR and suppresses …
WebChrysophanol is a unique anthraquinone having broad-spectrum therapeutic potential along with ecological importance. It is the first polyketide that has been reported to be … WebObjective: Chrysophanol is a natural anthraquinone, also known as chrysophanic acid and 1,8-dihydroxy-3-methyl-anthraquinone. It has been widely used in the food and …
WebOct 31, 2024 · Anthraquinones (AQs) are present in foods, dietary supplements, pharmaceuticals, and traditional treatments and have a wide spectrum of pharmacological activities. In the search for anti-cancer drugs, AQ derivatives are an important class. In this study, anthraquinone aglycons chrysophanol (Chr), emodin (EM) and FDA-approved …
WebMar 14, 2024 · et al.[36] found that chrysophanol was a potential inhibitor of P-glycoprotein under physiological conditions. Chrysophanol inhibits cell growth in several cancer cells … fish putterWebDec 15, 2024 · Objective: Chronic obstructive pulmonary disease (COPD) is a common respiratory disease characterized by the persistent airflow obstruction. Chrysophanol, an anthraquinone derivative isolated from the rhizomes of Rheum palmatum, has been reported to be protective for some inflammatory diseases.The present report aimed to dissect its … fish purse patternWebDec 1, 2024 · Chrysophanol, physcion, aloe-emodin and emodin were confirmed by GC–MS and the possible main cleavage pathways of fragment ions are discussed in this study. Rhubarb is a traditional Chinese medicinal herb which required an effective evaluation method to quantitate the four major active anthraquinone compounds described. The … canditonline mon compteWebChrysophanol is a well-known intermediate toward biosynthesis of xanthone type of compounds such as secalonic acids. 175 If looking at the structure of chrysophanol without any a priori knowledge of the biosynthesis of the compound, and in particular the functional groups of the A-ring of chrysophanol (Fig. 16), one could easily speculate that the core … fish purpleWebFeb 14, 2024 · Chrysophanol (CPH) is a 1, 8-dihydroxy-3-methyl derivative of the 9, 10-anthracenedion ring rst identi ed from rheum rhubarbarum to a herbaceous perrinary … fish put in lyeWeb49 rows · Aug 1, 2024 · Chrysophanol is a natural anthraquinone, also known as chrysophanic acid and 1,8-dihydroxy-3-methyl-anthraquinone. It has been widely … fish puttufish puttanesca